Dengue Virus Net is the web resource for anyone interested in dengue. Dengue is a mosquito-borne infection that causes a severe flu-like illness (dengue fever), and sometimes a potentially lethal complication called dengue haemorrhagic fever. Global incidence of dengue has grown dramatically in recent decades. About two fifths of the world's population are now at risk. Dengue is found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas. Dengue is transmitted to humans by the Aedes aegypti or more rarely the Aedes albopictus mosquito, which feed during the day. Dengue haemorrhagic fever is a leading cause of serious illness and death among children in some Asian countries. A vaccine for dengue fever has been approved by the FDA in May 2019 and is commercially available in a number of countries.

The objectives of Dengue Virus Net are to be the public and professional information resource for dengue and to serve as a network in the exchange of information and news related to dengue.

• 15 people have died from dengue fever this year - Dominican Today
  Tue, 09 Aug 2022 16:59 GMT
• Dengue fever in Miami-Dade County, Florida: 3rd local transmission reported - Outbreak News Today - Outbreak News Today
  Tue, 09 Aug 2022 19:47 GMT
• Changing mosquito genes, spreading bacteria: Science sees success vs dengue - INQUIRER.net
  Wed, 10 Aug 2022 09:47 GMT
• Outbreak update – Dengue fever in Afghanistan, 4 August 2022 - Afghanistan - ReliefWeb
  Fri, 05 Aug 2022 00:45 GMT
• How kids are winning the fight against dengue fever in a Rio favela - New Scientist
  Tue, 02 Aug 2022 15:00 GMT
• First human case of dengue in Florida spurs mosquito-borne illness advisory - New York Post
  Thu, 21 Jul 2022 07:00 GMT
• What is dengue and where did it originate from? - Health Desk
  Thu, 21 Jul 2022 17:02 GMT
• Dengue in Rohingya refugee/Forcibly Displaced Myanmar Nationals (FDMN) camps in Cox's Bazar - Bangladesh - World Health Organization
  Wed, 03 Aug 2022 15:19 GMT
• Temperature, Oceanic Niño Index May Predict Vector Activity and Dengue Fever Risk - Infectious Disease Advisor
  Fri, 15 Jul 2022 07:00 GMT
• Foods For Dengue: Eat These 8 Foods To Recover Quickly | TheHealthSite.com - TheHealthSite
  Wed, 10 Aug 2022 04:54 GMT
• Health Officials Issue Mosquito Borne Illness Advisory Following Confirmation of One Dengue Case | Florida Department of Health in Miami-Dade - Florida Department of Health in Miami-Dade County
  Mon, 18 Jul 2022 07:00 GMT
• Brazil: Minas Gerais reports nearly 60,000 confirmed dengue cases - Outbreak News Today - Outbreak News Today
  Tue, 09 Aug 2022 20:37 GMT
• Amid blackouts, food shortages, Cubans face a dengue outbreak that has killed two children - Miami Herald
  Wed, 20 Jul 2022 07:00 GMT
• Vietnam tells hospitals to prepare as dengue fever cases surge - Reuters.com
  Wed, 13 Jul 2022 07:00 GMT
• Philippines dengue tally tops 90,000, More than double the 2021 numbers - Outbreak News Today - Outbreak News Today
  Tue, 09 Aug 2022 19:59 GMT

• PRO/AH/EDR> Invasive mosquito - France (03): (BT)
  Mon, 06 Sep 2021 21:28:53 -0400
  Yellow Fever, Zika virus, Dengue, Chikungunya -- France
  A potentially deadly mosquito that can carry viruses such as yellow fever and Zika has been spotted in Brittany, northern France, sparking fears they may soon land on British shores. Asian tiger mosquitoes [_Aedes albopictus_] have been confirmed to be in the commune of Domagne in the department of Ile-et-Vilaine in western Brittany.
  Health authorities are preparing an intensive campaign to rid the area of the insects with strong insecticides.
  The creatures were 1st seen in France in the

• In silico testing of flavonoids as potential inhibitors of protease and helicase domains of dengue and Zika viruses Wed, 10 Aug 2022 06:00:00 -0400
  BACKGROUND: Dengue and Zika are two major vector-borne diseases. Dengue causes up to 25,000 deaths and nearly a 100 million cases worldwide per year, while the incidence of Zika has increased in recent years. Although Zika has been associated to fetal microcephaly and Guillain-Barré syndrome both it and dengue have common clinical symptoms such as severe headache, retroocular pain, muscle and join pain, nausea, vomiting, and rash. Currently, vaccines have been designed and antivirals have been...
• Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission? Tue, 09 Aug 2022 06:00:00 -0400
  Aedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which cause febrile, hemorrhagic, and neurological diseases and remain a major threat to global public health. The high ecological plasticity, opportunistic feeding patterns, and versatility in the use of urban and natural breeding sites of these vectors have favored their dispersal and adaptation in tropical, subtropical, and even...
• RNA In Situ Hybridization and Immunohistochemistry to Visualize Gene Expression in Peripheral Chemosensory Tissues of Mosquitoes Mon, 08 Aug 2022 06:00:00 -0400
  Mosquito-borne diseases such as malaria, Zika virus, and dengue virus are a menace to the human population. Although many mosquito species are not attracted to humans and do not feed on blood, human-biting female mosquitoes are strongly attracted to people and use chemosensory cues to identify a suitable host for a blood meal. Mosquitoes need blood components to reproduce, rendering them excellent vectors for blood-borne diseases. The three genera (Culex, Anopheles, and Aedes) responsible for...
• TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection Mon, 08 Aug 2022 06:00:00 -0400
  Transmembrane Protein 41B (TMEM41B) and Vacuole Membrane Protein 1 (VMP1) are two ER-associated lipid scramblases that play a role in autophagosome formation and cellular lipid metabolism. TMEM41B is also a recently validated host factor required by flaviviruses and coronaviruses. However, the exact underlying mechanism of TMEM41B in promoting viral infections remains an open question. Here, we validated that both TMEM41B and VMP1 are essential host dependency factors for all four serotypes of...
• Randomized single oral dose phase 1 study of safety, tolerability, and pharmacokinetics of Iminosugar UV-4 Hydrochloride (UV-4B) in healthy subjects Mon, 08 Aug 2022 06:00:00 -0400
  CONCLUSIONS/SIGNIFICANCE: UV-4 is a host-targeted broad-spectrum antiviral drug candidate. At doses in humans up to 1000 mg there were no serious adverse events reported and no subjects were withdrawn from the study due to treatment-emergent adverse events. These data suggest that therapeutically relevant drug levels of UV-4 can be safely administered to humans and support further clinical development of UV-4 hydrochloride or other candidate antivirals in the iminosugar class.
• Stress-Mediated Responses of Aedes aegypti (Diptera: Culicidae) Larvae When Exposed to Metarhizium brunneum (Hypocreales: Clavicipitaceae) and Toxorhynchites brevipalpis (Diptera: Culicidae) Mon, 08 Aug 2022 06:00:00 -0400
  Aedes aegypti mosquitoes are capable of vectoring a wide range of diseases including dengue, yellow fever, and Zika viruses, with approximately half of the worlds' population at risk from such diseases. Development of combined predator-parasite treatments for the control of larvae consistently demonstrates increased efficacy over single-agent treatments, however, the mechanism behind the interaction remains unknown. Treatments using the natural predator Toxorhynchites brevipalpis and the...
• Changing Spectrum of Acute Encephalitis Syndrome in India and a Syndromic Approach Mon, 08 Aug 2022 06:00:00 -0400
  Acute encephalitis syndrome (AES) refers to an acute onset of fever and clinical neurological manifestation that includes mental confusion, disorientation, delirium, or coma, which may occur because of infectious or non-infectious causes. Cerebrospinal fluid (CSF) pleocytosis generally favors infectious etiology, and a normal CSF favors an encephalopathy or non-infectious AES. Among the infectious AES, viral, bacterial, rickettsial, fungal, and parasitic causes are the commonest. Geographical...
• Significance of Neuronal Autoantibodies in Comparison to Infectious Etiologies among Patients Presenting with Encephalitis in a Region with a High Prevalence of Infections Mon, 08 Aug 2022 06:00:00 -0400
  CONCLUSIONS: Identified infectious forms of meningoencephalitis (44.4%) greatly exceeded the occurrence of neuronal autoantibodies (9.1%) and AE (2%) in Sri Lanka, and this may be common in those regions where infections are prevalent.
• Impact of Antecedent Infections on the Antibodies against Gangliosides and Ganglioside Complexes in Guillain-Barré Syndrome: A Correlative Study Mon, 08 Aug 2022 06:00:00 -0400
  BACKGROUND AND AIMS: Guillain-Barré Syndrome (GBS), an immune-mediated neuropathy, is characterized by antibodies against gangliosides/ganglioside complexes (GSCs) of peripheral nerves. Antecedent infections have been reported to induce antibodies that cross-react with the host gangliosides and thereby have a pivotal role in conferring an increased risk for developing GBS. Data pertaining to the impact of various antecedent infections, particularly those prevalent in tropical countries like...
• Effect of School-Based Educational Interventions on the Knowledge of Malaria and Dengue Among Higher Secondary School Children in Chennai, India: A Pre and Post-intervention Study Mon, 08 Aug 2022 06:00:00 -0400
  CONCLUSION: School-based educational interventions had a significant impact on enhancing the knowledge on the prevention and control of malaria and dengue among school children. Involving school children can strengthen existing malaria and dengue prevention and control strategies in endemic areas.